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Synovial sarcoma, a malignant soft tissue tumor, is thought to be a high grade sarcoma. It primarily occurs in close association with tendon sheath, bursae, and joint capsule. Twenty-five cases of synovial sarcoma which had been treated between December 1985 and April 1995 were reviewed. There were 15 females and 10 males. The average age of the patients was 39.3 years(range 9 to 60). The average follow-up was 39.2 months(range, 7 to 93). Seventeen cases had the excision of the mass performed in another hospital before visiting our hospital and 7 cases had distant metastasis. Five amputations, 16 wide excisions, and 3 marginal excisions were done. Chemotherapy, radiotherapy, and their combination were performed after surgery. Six cases were treated with wide excision and radiotherapy and one of them had distant metastasis. Five cases were treated with a combination of wide excision and radiotherapy and chemotherapy. One of them had distant metastasis. Marginal excision and radiotherapy was performed in one case. Three cases were treated with amputation and 1 of them had local recurrence. In total, 7 of 25 cases, including 4 cases which had metastasis at the 1st visit, died due to metastasis. 5-year survival rate was 81% and median survival was 42.7 months. Age over 20 and tumor size over 5cm could be considered to be unfavorable prognostic factors but no statistic significance was found.
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